Narcolepsy as an Immune-Mediated Disease
نویسندگان
چکیده
منابع مشابه
Narcolepsy as an Immune-Mediated Disease
Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, hypnagonic hallucinations, sleep paralysis, and disturbed nocturnal sleep patterns. This disease is secondary to the specific loss of hypothalamic hypocretin (orexin)-producing neurons in the lateral hypothalamus. An autoimmune basis for the disease has long been suspected based on its strong associa...
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The link between oncology and immunology has a long history and its development is forced by the necessity to develop innovative and highly efficient modalities for immunological destruction of malignant cells. The limited efficacy of surgery, chemotherapy and radiation also exemplify these issues, as these treatments do not eliminate all cancerous cells, do not address the immunosuppressive na...
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Fibrosing colonopathy, a recently described complication of patients with cystic fibrosis, manifests clinically approximately 7-12 months after starting high dose pancreatic enzyme treatment. Although the pathogenesis of fibrosing colonopathy is unknown, it is highly correlated with pancreatic enzyme dose. In this study, immune mediated factors which may be associated with fibrosing colonopathy...
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10.2217/FNL.09.57 © 2009 Future Medicine Ltd The brain has long been considered immuneprivileged and protected from peripheral immune insults by the BBB. Indeed, few autoimmune diseases are known to affect the brain parenchyma when compared with the impressive list of autoimmune conditions targeting virtually every organ of the body. These autoimmune diseases can typically be divided into organ...
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ژورنال
عنوان ژورنال: Sleep Disorders
سال: 2014
ISSN: 2090-3545,2090-3553
DOI: 10.1155/2014/792687